|
|
|
|
|
|
Research Activities
|
|
Seema S. Aceves, M.D., Ph.D.
| - |
Study of eosinophilic esophagitis: its pathogenesis (the role of pro-inflammatory and pro-fibrotic molecules), diagnosis (biomarker discovery) and treatment (topical budesonide) |
| - |
A randomized, placebo-controlled trial of oral viscous budesonide versus proton pump inhibito therapy in pediatric eosinophilic esophagitis |
| - |
Multi-center clinical trials on the use of anti-IL-5 in pediatric eosinophilic esophagitis |
| - |
Principal investigator, San Diego County study of the clinical characteristics of eosinophilic esophagitis |
| - |
Executive Counsel member, The International Gastrointestinal Eosinophil Reserch network |
John F. Bastian, M.D.
| - |
Difficult asthma |
| - |
Immunodeficiency disorders |
| - |
Kawasaki disease |
Jane C. Burns, M.D.
| - |
The pathophysiology, immunology, diagnosis, etiology, treatment, genetics, epidemiology and history of Kawasaki disease |
| - |
A multicenter, randomized placebo-controlled clinical trial of infliximab plus IVIG for primary treatment of Kawasaki disease |
| - |
Call-back study of adolescents and young adults with a history of Kawasaki disease in childhood |
Alessandra M. Franco, M.D., Ph.D.
| - |
Cytotoxic T cell biology |
| - |
Carbohydrate T cell recognition |
| - |
Designer glycopeptides containing tumor-associated carbohydrate antigens as vaccines for prevention/treatment of epithelial cancer |
| - |
Epitope glycosylation to bypass the effects of viral mutations (HIV and HBV as models) in antiviral vaccines |
| - |
T-cell repertoire in Kawasaki disease |
Hal M. Hoffman, M.D.
| - |
Role of innate immunity in autoinflammatory disorders |
| - |
Genetic basis of familial cold autoinflammatory syndrome (FCAS) and other cryopyriopathies |
| - |
Role of IL-1 targeted therapy in cryopyrinopathy patients (has resulted in an effective new therapy for these patients.) |
| - |
Primary consultant, a multicenter, phase III trial of IL-1 TRAP, a novel IL-1 blocker in 40-50 FCAS patients in North America |
| - |
Genetic basis of rare inherited disorders including congenital diarrheas, rare urticarial disorders, and autoinflammatory disorders |
| - |
Inflammatory mechanisms involved in periodic fever disorders of childhood |
Anthony A. Horner, M.D.
| - |
Characterization of the molecular content and immunological activities of sterile house dust extracts to better define the immunomodulatory role living environments have on the genesis of allergic diseases |
| - |
Translational studies to determine if house dust extract bioactivities are predictive of the intrinsic allergic risk associated with being raised in their homes of origin |
| - |
Treatment of allergic diseases with toll-like receptor ligands and other immunomodulatory molecules |
Chisato Shimizu, Ph.D.
| - |
Genetics and molecular pathogenesis of Kawasaki disease |
Ilona S. Szer, M.D.
| - |
Conducts several clinical trials of new treatments for juvenile arthritis and pediatric rheumatologic diseases |
Robert M. Sheets, M.D.
| - |
Clinical trials of new treatments for pediatric rheumatologic diseases, currently involved in the TREAT study |
|
|
|
|
|
|
|
|
|